1H-Indole-4-carboxylic acid, 3-cyano-, methyl ester

1H-Indole-4-carboxylic acid, 3-cyano-, methyl ester - Names and Identifiers

Name	Methyl 3-cyanoindole-4-carboxylate
Synonyms	Methyl 3-cyanoindole-4-carboxylate Methyl 3-cyano-1H-indole-4-carboxylate 3-Cyano-1H-indole-4-carboxylic acid methyl ester 3-Cyano-1H-indole-4-carboxylic acid methyl ester 1H-Indole-4-carboxylic acid, 3-cyano-, methyl ester
CAS	939793-19-8
InChI	InChI=1/C11H8N2O2/c1-15-11(14)8-3-2-4-9-10(8)7(5-12)6-13-9/h2-4,6,13H,1H3

1H-Indole-4-carboxylic acid, 3-cyano-, methyl ester - Physico-chemical Properties

Molecular Formula	C11H8N2O2
Molar Mass	200.19
Density	1.33g/cm³
Melting Point	>140°C (dec.)
Boling Point	413.5°C at 760 mmHg
Flash Point	203.9°C
Solubility	Chloroform, Methanol (Slightly)
Vapor Presure	4.79E-07mmHg at 25°C
Appearance	Solid
Color	Light Beige to Beige
Storage Condition	2-8°C
Refractive Index	1.639

1H-Indole-4-carboxylic acid, 3-cyano-, methyl ester - Introduction

Methyl 3-cyanoindole-4-carboxylate is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless or light yellow crystal
-Molecular formula: C12H9NO2
-Molecular Weight: 199.21
-melting point: 90-93 ℃
-Boiling point: 338.2 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol and dimethyl sulfite
-Chemical reaction: The compound can be hydrolyzed to indolone and carbon dioxide under acidic conditions.

Use:
- Methyl 3-cyanoindole-4-carboxylate is an important organic synthesis intermediate, commonly used in the preparation of indole compounds.
-It can be used as a starting material for drug synthesis, and also for the synthesis of pesticides and dyes.

Method:
- Methyl 3-cyanoindole-4-carboxylate can be prepared by reacting indole with methyl cyanoformate. The specific preparation method may be reacting indole with methyl cyanoformate under alkaline conditions to generate the target product.

Safety Information:
- Methyl 3-cyanoindole-4-carboxylate has no clear hazard report under normal use conditions.
-When performing laboratory procedures, follow general chemical laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and goggles.
-During storage and transportation, it should be kept in a dry, well-ventilated place, away from fire and oxidizing agents.

Last Update：2024-04-09 02:00:49